Problem: Triglyceride Interference

The percentage of 4797 normal and dyslipidemic adults at three different ranges of triglyceride levels in whom LDL cholesterol valued estimated by the Friedewald were not within 10% of LDL cholesterol values obtained by beta quantification.

Adapted from McNamara JR, Cohn JS, Wilson PWF, Schaefer EJ. Calculated values for low-density lipoprotein cholesterol in the assessment of lipid abnormalities and coronary disease risk. Clin Chem. 1990;36(1):36-42.